Mechanisms of antimicrobial resistance in bacterial isolates from livestock

Antimicrobial resistance (AMR) in bacteria isolated from livestock poses a significant threat to public health. This study aims to elucidate the mechanisms driving AMR in bacterial isolates from livestock, with implications for both animal and human health. A comprehensive literature review was conducted to identify key studies investigating AMR in livestock-associated bacteria. Molecular techniques, including whole-genome sequencing and plasmid analysis, were employed to characterize resistance genes and their mobility among bacterial populations. Selective pressure from antimicrobial usage in agricultural settings was identified as a primary driver of AMR in livestock-associated bacteria. Horizontal gene transfer, facilitated by mobile genetic elements such as plasmids and integrons, plays a crucial role in disseminating resistance genes among bacterial populations. This study underscores the interconnectedness of agricultural and clinical settings in the emergence and dissemination of AMR. Effective antimicrobial stewardship practices, alternative disease prevention strategies, and enhanced surveillance programs are essential for mitigating the spread of AMR in livestock populations and safeguarding public health.

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