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Discovery of bioactive peptides as therapeutic agents for skin wound repair


Citation

Md Fadilah, Nur Izzah and Shahabudin, Nurul Aqilah and Mohd Razif, Raniya Adiba and Sanyal, Arka and Ghosh, Anushikha and Baharin, Khairul Idzwan and Ahmad, Haslina and Maarof, Manira and Motta, Antonella and Fauzi, Mh Busra (2024) Discovery of bioactive peptides as therapeutic agents for skin wound repair. Journal of Tissue Engineering, 15 (undefined). art. no. undefined. undefined-undefined. ISSN ; eISSN: 2041-7314

Abstract

Short sequences of amino acids called peptides have a wide range of biological functions and the potential to treat a number of diseases. Bioactive peptides can be derived from different sources, including marine organisms, and synthetic design, making them versatile candidates for production of therapeutic agents. Their therapeutic effects span across areas such as antimicrobial activity, cells proliferation and migration, synthesis of collagen, and more. This current review explores the fascinating realm of bioactive peptides as promising therapeutic agents for skin wound healing. This review focuses on the multifaceted biological effects of specific peptides, shedding light on their potential to revolutionize the field of dermatology and regenerative medicine. It delves into how these peptides stimulate collagen synthesis, inhibit inflammation, and accelerate tissue regeneration, ultimately contributing to the effective repair of skin wounds. The findings underscore the significant role several types of bioactive peptides can play in enhancing wound healing processes and offer promising insights for improving the quality of life for individuals with skin injuries and dermatological conditions. The versatility of peptides allows for the development of tailored treatments catering to specific wound types and patient needs. As continuing to delve deeper into the realm of bioactive peptides, there is immense potential for further exploration and innovation. Future endeavors may involve the optimization of peptide formulations, elucidation of underlying molecular and cellular mechanisms.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
DOI Number: https://doi.org/10.1177/20417314241280359
Publisher: SAGE Publications Ltd
Keywords: biological effect; Peptide; skin; therapeutic agent; tissue repair; wound healing
Depositing User: Ms. Azian Edawati Zakaria
Date Deposited: 01 Oct 2025 04:36
Last Modified: 30 Oct 2025 04:14
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1177/20417314241280359
URI: http://psasir.upm.edu.my/id/eprint/120422
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