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ANCA- associated vasculitis with pulmonary-renal syndrome in the elderly: a case report and review


Citation

Md Shah, Anim and Hashim, Uswaton Hasanah and Mohd Aris, Nur Alfalailah and Chai, Peng Ban and Sharif, Sherillia Affah and Peraba, Premila (2024) ANCA- associated vasculitis with pulmonary-renal syndrome in the elderly: a case report and review. MJM Case Reports Journal, 3 (3). pp. 163-166. ISSN 2948-3859

Abstract

We present a case of a 67-year-old Chinese male who presented with acute kidney injury and nephrotic syndrome. The patient subsequently developed pulmonary hemorrhage, and his serum myeloperoxidase and proteinase 3 tests were positive, indicating ANCA-associated vasculitis. Due to the rapid progression of his clinical condition, treatment was initiated with plasma exchange and intravenous immunoglobulin, alongside induction therapy with high-dose glucocorticoids. Renal biopsy was not performed due to multiple challenges. During his two-month hospital stay, the patient required hemodialysis at least twice a week and received standard treatment of care. Despite the aggressive treatment approach, the patient continued to exhibit signs of renal insufficiency, necessitating ongoing supportive care and monitoring.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Medical Journal Of Malaysia
Keywords: Anca-associated vasculitis; Pulmonary-renal syndrome; Elderly; Case report; Review; Acute kidney injury; Nephrotic syndrome; Pulmonary hemorrhage; Myeloperoxidase; Proteinase 3; Plasma exchange; Intravenous immunoglobulin; Glucocorticoids; Renal biopsy; Hemodialysis.
Depositing User: MS. HADIZAH NORDIN
Date Deposited: 19 Feb 2026 00:27
Last Modified: 19 Feb 2026 00:27
URI: http://psasir.upm.edu.my/id/eprint/119933
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