Anti-glomerular basement membrane (anti-GBM) disease: the challenges in diagnosis and the choice of treatment

Citation

Li, Li Kwan and Lim, Christopher Thiam Seong and Yong, Fatt Cheng and Abd Ghani, Fauzah and Ramli, Raihan (2024) Anti-glomerular basement membrane (anti-GBM) disease: the challenges in diagnosis and the choice of treatment. Journal of Clinical and Translational Nephrology, 1. ISSN 2710-5903

Abstract

Anti–glomerular basement membrane (anti-GBM) antibody disease is an autoimmune disorder. The majority of patients develop widespread glomerular crescent formation, presenting with features of rapidly progressive glomerulonephritis (RPGN). The etiology is unclear. The treatment depends on the creatinine level at presentation, dialysis dependency, and pulmonary involvement to decide on plasmapheresis, glucocorticoid, and immunosuppressive therapy. We report a case of a 17-year-old lady who presented features of RPGN requiring intermittent dialysis, renal biopsy, and serology showing features of anti-GBM glomerulonephritis (GN).

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Additional Metadata

Item Type:	Article
Divisions:	Faculty of Medicine and Health Science
Publisher:	Malaysian Society of Nephrology
Keywords:	Anti-gbm disesase; Glomerulonephritis; Rapid progressive glomerulonephritis; End stage kidney disease
Depositing User:	MS. HADIZAH NORDIN
Date Deposited:	16 Feb 2026 08:16
Last Modified:	16 Feb 2026 08:16
URI:	http://psasir.upm.edu.my/id/eprint/119854
Statistic Details:	View Download Statistic

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