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Epstein-Barr virus-associated smooth muscle tumour: two case reports


Citation

Hussin, Huzlinda and Abdul Kahar, Nor Farahin and Mohd Dusa, Noraini and Abd Rani, Nor Haizura (2024) Epstein-Barr virus-associated smooth muscle tumour: two case reports. Malaysian Journal of Medicine and Health Sciences, 20 (suppl.11). pp. 102-105. ISSN 1675-8544; eISSN: 2636-9346

Abstract

Epstein-Barr virus-associated smooth muscle tumour (EBV-SMT) is an intermediate mesenchymal neoplasm recognised in immunocompromised patients, including HIV-infected patients. EBV-SMT is challenging to diagnose since it occurs in various age groups and anatomical sites and presents with nonspecific symptoms. The diagnosis is further complicated by the similarity of its histopathological features with other spindle cell tumours. A clinical history of immunosuppression, immunohistochemistry study and association with Epstein-Barr. virus (EBV) infection can aid in the diagnosis. Here, we reported two cases of EBV-SMT in two patients with HIV infection, emphasising the histomorphology features and immunohistochemical profile that help in the diagnosis.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: EBV infections; EBV nuclear antigen; Epstein-Barr virus; Smooth muscle tumour; Immunocompromised patient
Depositing User: Ms. Che Wa Zakaria
Date Deposited: 18 Jun 2025 08:17
Last Modified: 18 Jun 2025 08:17
URI: http://psasir.upm.edu.my/id/eprint/117973
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