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Mycobacterium senegalense catheter-related bloodstream infection


Citation

Amin Nordin, Syafinaz and Badarol Hisham, Noralwani and Masri, Siti Norbaya and Madon, Mazriza (2024) Mycobacterium senegalense catheter-related bloodstream infection. BMJ Case Reports, 17 (4). art. no. e259761. ISSN 1757-790X

Abstract

Catheter-related bloodstream infection (CRBSI) is one of the common healthcare-acquired infections imposing a high burden of morbidity and mortality on the patients. Non-tuberculous mycobacterium is a rare aetiology for CRBSI and poses challenges in laboratory diagnosis and clinical management. This is a case of a woman in her early 60s with underlying end-stage renal failure, diabetes mellitus and hypertension presented with a 2-week history of high-grade fever postregular haemodialysis, vomiting, lethargy and altered mental status. Blood cultures from a permanent catheter and peripheral taken concurrently yielded Mycobacterium senegalense, identified by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry, which established the diagnosis of CRBSI atypically presented with concurrent acute intracranial bleeding and cerebrovascular infarction at initial presentation. She was started on a combination of oral azithromycin, oral amikacin and intravenous imipenem, and the permanent catheter was removed. Despite the treatments instituted, she developed septicaemia, acute myocardial infarction and macrophage activation-like syndrome, causing the patient’s death.


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Official URL or Download Paper: https://casereports.bmj.com/content/17/4/e259761

Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Institute of Bioscience
Hospital Pengajar UPM
Publisher: BMJ Publishing Group
Keywords: Chronic renal failure; Nosocomial infections
Depositing User: Ms. Che Wa Zakaria
Date Deposited: 14 May 2025 06:13
Last Modified: 14 May 2025 06:13
URI: http://psasir.upm.edu.my/id/eprint/117324
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