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Enzymatic synthesis of galactosylkojic acid with immobilized β-galactosidase from bacillus circulans


Citation

Ali Hassan, Mohd. and Ismail, Fadhilah and Yamamoto, Shuichi and Yamada, Hidenori and Nakanishi, Kazuhiro (1995) Enzymatic synthesis of galactosylkojic acid with immobilized β-galactosidase from bacillus circulans. Bioscience, Biotechnology and Biochemistry, 59 (3). pp. 543-545. ISSN 0916-8451; eISSN: 1347-6947

Abstract

Galactosylkojic acid, in which the hydroxymethyl group of the kojic acid moiety is β-galactosylated, was synthesized by using a transgalactosidation reaction with an immobilized β-galactosidase from Bacillus circulans. With 5% kojic acid and 20% lactose as the substrates, the yield with respect to the initial amount of kojic acid was around 24% as a maximum. The inhibitory effect of galactosylkojic acid towards the oxidation reaction of L-β-(3,4-dihydroxyphenyl)alanine (L-DOPA) with tyrosinase was similar to that of kojic acid.


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Additional Metadata

Item Type: Article
Divisions: Universiti Pertanian Malaysia
DOI Number: https://doi.org/10.1271/bbb.59.543
Publisher: Taylor & Francis Group LLC
Keywords: Galactosylkojic acid; Enzymatic synthesis; Immobilized β-galactosidase; Bacillus circulans; Transgalactosidation; Kojic acid
Depositing User: Ms. Zaimah Saiful Yazan
Date Deposited: 22 Apr 2025 06:36
Last Modified: 22 Apr 2025 06:36
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1271/bbb.59.543
URI: http://psasir.upm.edu.my/id/eprint/116991
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