Candida glabrata gene expression response upon engulfment by THP-1 macrophages

Citation

Ismail, Elysha Nur and Than, Leslie Thian Lung (2024) Candida glabrata gene expression response upon engulfment by THP-1 macrophages. In: 14th Malaysian Symposium of Biomedical Science 2024, 1-2 Jun. 2024, Universiti Putra Malaysia, Serdang. . (Submitted)

Abstract

Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata during macrophage interaction to understand its adaptive strategies against the host immune system, specifically focusing on genes linked to altered metabolism and cell wall modifications. The rise in multidrug-resistant C. globroto strains limits treatment options, necessitating a congrefensive understanding of its gone functions and interactions.

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Additional Metadata

Item Type:	Conference or Workshop Item (Poster)
Divisions:	Faculty of Medicine and Health Science
Keywords:	Candida glabrata; THP-1 macrophages; Gene expression
Depositing User:	Mr. Mohamad Syahrul Nizam Md Ishak
Date Deposited:	06 Mar 2025 01:55
Last Modified:	06 Mar 2025 02:25
URI:	http://psasir.upm.edu.my/id/eprint/115493
Statistic Details:	View Download Statistic

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