Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase

Citation

Lee, K.H. and Lee, P.M. and Siaw, Y.S. and Morihara, K. (1992) Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase. Biotechnology Letters, 14 (9). pp. 779-784. ISSN 0141-5492; eISSN: 1573-6776

Abstract

Pseudomonas elastase was found to be efficient in catalysing the reaction between N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester producing the aspartame precursor in aqueous and aqueous methanolic solutions. 25% (v/v) methanol was most favourable for the synthesis where about 100% increase in yield was obtained compared to that in aqueous solution.

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Additional Metadata

Item Type:	Article
Divisions:	Universiti Pertanian Malaysia
DOI Number:	https://doi.org/10.1007/BF01029138
Publisher:	Kluwer Academic Publishers
Keywords:	Aspartame precursor; Aqueous-methanolic; Enzyme catalysis; Pseudomonas aeruginosa elastase; Synthesis
Depositing User:	Mohamad Jefri Mohamed Fauzi
Date Deposited:	13 Feb 2025 03:16
Last Modified:	13 Feb 2025 03:17
Altmetrics:	http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1007/BF01029138
URI:	http://psasir.upm.edu.my/id/eprint/114968
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