Citation
Tofazzal, M. and Tarafder, H. and Ali, Manaf A. and Saravanan, N.
(2000)
Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate.
Transition Metal Chemistry, 25 (3).
pp. 295-298.
ISSN 0340-4285; eISSN: 0340-4285
Abstract
Two tridentate Schiff bases having ONS and NNS donor sequences were prepared by condensing S-benzyldithiocarbazate (NH2NHCSSCH2Ph) (SBDTC) with pyridine-2-carboxaldehyde and salicylaldehyde, respectively. Complexes of these ligands with NiII, ZnII, CrIII, CoII, CuII, and SnII were studied and characterized by elemental analyses and various physico-chemical techniques. NiII, CuII, ZnII and SnII complexes were four-coordinate while the CrIII, SrIII and CoIII complexes were six-coordinate. The ONS Schiff base was moderately active against leukemia, while its zinc, antimony and cobalt complexes were strongly active against leukemic cells with DC50 = 0.35-5.00.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Science |
| DOI Number: | https://doi.org/10.1023/A:1007044910814 |
| Publisher: | Kluwer Academic Publishers |
| Keywords: | Coordination chemistry; Schiff bases; Tridentate ligands; Antimicrobial activity; Leukemia; Metal complexes |
| Depositing User: | Ms. Zaimah Saiful Yazan |
| Date Deposited: | 15 Jan 2025 07:59 |
| Last Modified: | 15 Jan 2025 07:59 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1023/A:1007044910814 |
| URI: | http://psasir.upm.edu.my/id/eprint/114457 |
| Statistic Details: | View Download Statistic |
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