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Subtyping of Properdin Factor B (Bf) by Isoelectrofocusing


Citation

Teng, Y.-S. and Tan, S.G. (1982) Subtyping of Properdin Factor B (Bf) by Isoelectrofocusing. Human Heredity, 32 (5). pp. 362-366. ISSN 0001-5652; eISSN: 1423-0062

Abstract

Properdin factor B (Bf) is a polymorphic protein in the human plasma. Two common alleles, BfS, BfF, and two rare alleles, BfF1, BfS1, have been demonstrated in Caucasians. We now report that BfF can be subtyped into two alleles, BfFa and BfFb by isoelectrofocusing. Family studies indicate that they are inherited in a co-dominant pattern. Gene frequencies for Caucasians are: BfS 0.808, BfF1 0.019, Bfs1 0.005, Bfs1 0.038 and BfFa 0.128.


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Additional Metadata

Item Type: Article
Divisions: Universiti Pertanian Malaysia
DOI Number: https://doi.org/10.1159/000153323
Publisher: Karger Publishers
Keywords: Agarose isoelectrofocusing; Bf polymorphism; Caucasians; Codominance; Family studies; Human plasma; Subtyping
Depositing User: Ms. Zaimah Saiful Yazan
Date Deposited: 06 Mar 2025 08:01
Last Modified: 06 Mar 2025 08:01
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1159/000153323
URI: http://psasir.upm.edu.my/id/eprint/112474
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