Citation
Ali, A. and McKeen, M. and Hamid, M. and Aun, Q. and Zauyah, Y. and Azimahtol, H. and Kawazu, K.
(1997)
Cytotoxicity and electron microscopy of cell death induced by goniothalamin.
Planta Medica, 63 (1).
pp. 81-83.
ISSN 0032-0943; eISSN: 1439-0221
Abstract
The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultra-structural level, goniothalamin-induced cytotoxicity revealed a necrotic mode of cell death towards MCF-7 cells.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Food Science and Biotechnology Universiti Pertanian Malaysia |
| DOI Number: | https://doi.org/10.1055/s-2006-957611 |
| Publisher: | Georg Thieme Verlag KG |
| Keywords: | Cell Death; Electron Microscopy; Goniothalamin; Cytotoxicity |
| Depositing User: | Ms. Zaimah Saiful Yazan |
| Date Deposited: | 03 Mar 2025 01:33 |
| Last Modified: | 03 Mar 2025 01:33 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1055/s-2006-957611 |
| URI: | http://psasir.upm.edu.my/id/eprint/111947 |
| Statistic Details: | View Download Statistic |
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