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In vitro antifilarial effects of three plant species against adult worms of subperiodic Brugia malayi


Citation

M.Z., Zaridah and Idid, S.Z. and Wan Omar, A. and S., Khozirah (2001) In vitro antifilarial effects of three plant species against adult worms of subperiodic Brugia malayi. Journal of Ethnopharmacology, 78 (1). pp. 79-84. ISSN 0378-8741; eISSN: 1872-7573

Abstract

Five aqueous extracts from three plant species, i.e., dried husks (HX), dried seeds (SX) and dried leaves (LX) of Xylocarpus granatum (Meliaceae), dried stems (ST) of Tinospora crispa (Menispermaceae) and dried leaves (LA) of Andrographis paniculata (Acanthaceae) were tested in vitro against adult worms of subperiodic Brugia malayi. The relative movability (RM) value of the adult worms over the 24-h observation period was used as a measure of the antifilarial activity of the aqueous extracts. SX extract of X. granatum demonstrated the strongest activity, followed by the LA extract of A. paniculata, ST extract of T. crispa, HX extract and LX extract of X. granatum.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1016/s0378-8741(01)00286-0
Publisher: Elsevier
Keywords: Xylocarpus granatum; Tinospora crispa; Andrographis paniculata; Antifilarial effect; Relative movability(RM) value
Depositing User: Ms. Zaimah Saiful Yazan
Date Deposited: 11 Mar 2025 06:33
Last Modified: 11 Mar 2025 06:33
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/s0378-8741(01)00286-0
URI: http://psasir.upm.edu.my/id/eprint/111946
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