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The numerical analysis of non-newtonian blood flow in a mechanical heart valve


Citation

Chen, Aolin and Basri, Adi Azriff and Ismail, Norzian and Ahmad, Kamarul Arifin (2022) The numerical analysis of non-newtonian blood flow in a mechanical heart valve. Processes, 11 (1). pp. 1-19. ISSN 2227-9717

Abstract

Background: The non-physiological structure of mechanical heart valves (MHVs) affects the blood flow field, especially the complex microstructure at the hinge. Numerous studies suggest that the blood flow field in the aortic area with an MHV can be considered Newtonian. However, the Newtonian assumption is occasionally unreasonable, where blood viscosity changes with shear rate, exhibiting non-Newtonian shear-thinning characteristics. Methods: In this research, a comprehensive study of the non-Newtonian effects on the hemodynamic behavior of MHVs was performed. The impact of the Newtonian hypothesis was investigated on the internal hemodynamics of MHVs. Several non-Newtonian and Newtonian models were used to analyze the chamber flow and blood viscosity. MHVs were modeled and placed in simplified arteries. After the unstructured mesh was generated, a simulation was performed in OpenFOAM to analyze its hemodynamic parameters. Results: In the study of the non-Newtonian viscosity model, the Casson model differs significantly from the Newtonian model, resulting in a 70.34% higher wall shear stress. In the modified Cross and Carreau models, the non-Newtonian behavior can significantly simulate blood in the MHV at different stages during initial and intermediate deceleration. The narrowing of the hinge region in particular, has a significant impact on evaluating blood rheology. The low flow rate and high wall shear force at the hinge can cause blood cell accumulation and injury time, resulting in hemolytic thrombosis. Conclusion: The results exhibit that the Newtonian hypothesis underestimates the hemodynamics of MHVs, whose complex structure leads to increased recirculation, stagnation, and eddy current structure, and a reasonable choice of blood viscosity model may improve the result accuracy. Modfied Cross and Carreau viscosity models effectively exhibit the shear-thinning behavior in MHV blood simulations.


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Official URL or Download Paper: https://www.mdpi.com/2227-9717/11/1/37

Additional Metadata

Item Type: Article
Divisions: Faculty of Engineering
Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.3390/pr11010037
Publisher: Multidisciplinary Digital Publishing Institute
Keywords: Mechanical heart valve; Non-Newtonian viscosity model; Wall shear stress; Computational fluid dynamics
Depositing User: Ms. Zaimah Saiful Yazan
Date Deposited: 03 Sep 2024 07:25
Last Modified: 03 Sep 2024 07:25
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/pr11010037
URI: http://psasir.upm.edu.my/id/eprint/110242
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