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The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude


Citation

Shaharuddin, Shazreen and Nik Abd Rahman, Nik Mohd Afizan and Masarudin, Mas Jaffri and N Alamassi, Mohammedarfat (2023) The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude. Aeronautics and Aerospace Open Access Journal, 7 (4). 132- 133. ISSN 2576-4500

Abstract

The episode of prolonged exposure to high altitude can cause hypoxia and potential significant health consequences. In people with high altitude disorder, the body reaction to high altitudes starts with the formation of a protein called hypoxia-inducible factor (HIF), which triggers a series of other physiological changes and plays a central role in the hypoxia response; its activity is regulated by the oxygen-dependent degradation of the HIF-1α protein. This deserving condition provides an opportunity to study the effect of low oxygen tension of flying at high altitude that could lead to hypoxia using hypoxia sensor.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.15406/aaoaj.2023.07.00182
Publisher: MedCrave Group
Keywords: Hypoxia sensors; Biomarker; High altitude
Depositing User: Ms. Nur Faseha Mohd Kadim
Date Deposited: 17 Oct 2024 03:36
Last Modified: 17 Oct 2024 03:36
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.15406/aaoaj.2023.07.00182
URI: http://psasir.upm.edu.my/id/eprint/108978
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