Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide

Citation

Mohamed, Rafeezul and Ramli, Muhammad Mahyiddin and Reshak, Ali H. and Osman, Nurul Huda and Aziz, Mohd Yusmaidie and Mansor, Mohd Syahir (2023) Revolutionizing cancer treatment by boosting dendritic cell vaccine efficacy with graphene oxide. Trends in Immunotherapy, 7 (1). art. no. 2039. pp. 1-13. ISSN 2573-5985

Abstract

Dendritic cells (DCs) are potent antigen presenting cells that play a crucial role in stimulating T cell responses against cancer. DC vaccines have been utilized as an immunotherapy approach for cancer treatment, but their effectiveness is hampered by challenges in the tumor microenvironment. Graphene oxide (GO), a cutting-edge carbon-based nanomaterial, has shown promise in modulating DC activation and function. This review highlights the recent advancements in DC vaccines and explores how GO can enhance their efficacy for cancer treatment. By leveraging the unique properties of GO, such as its biocompatibility and immunomodulatory effects, DC vaccines can potentially be optimized to overcome the limitations of the tumor microenvironment and achieve improved outcomes in cancer immunotherapy.

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Additional Metadata

Item Type:	Article
Divisions:	Faculty of Science
DOI Number:	https://doi.org/10.24294/ti.v7.i1.2039
Publisher:	EnPress Publisher
Keywords:	Dendritic cells; Dc vaccine; Immunotherapy; Graphene oxide; Cancer; Good health and well-being
Depositing User:	Ms. Che Wa Zakaria
Date Deposited:	11 Oct 2024 08:27
Last Modified:	11 Oct 2024 08:27
Altmetrics:	http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.24294/ti.v7.i1.2039
URI:	http://psasir.upm.edu.my/id/eprint/108811
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