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Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis


Citation

Ho, Chai-Ling (2023) Comparative genomics analysis of Ganoderma orthologs involved in plant-pathogenesis. Forests, 14 (3). art. no. 653. pp. 1-20. ISSN 1999-4907

Abstract

Ganoderma species are producers of bioactive secondary metabolites and lignin degraders. A few Ganoderma species are known to be plant pathogens that attack economically important trees. In this study, comparative genomics analysis was conducted on the proteome of ten Ganoderma species/strains, focusing on the proteins that have been reported to be involved in plant-pathogenesis in other fungi. Fungal trophic lifestyle prediction of these Ganoderma species/strains supported that G. boninense (a potent pathogen to oil palm) is a hemibiotrophic fungus while the other Ganoderma species/strains analyzed were predicted to be saprophytes or a symbiont based on their Carbohydrate-Active Enzyme (CAZyme) contents. Although these Ganoderma species/strains were demonstrated to share many CAZymes and secondary metabolite core gene clusters, individual species may produce unique CAZymes and secondary metabolite core genes that determine their lifestyles, host-specificity, and potential as a producer of bioactive secondary metabolites. Ortholog groups that are related to fungal virulence from seven Ganoderma species/strains including those involved in lignin degradation, mycotoxin, siderophore and ergosterol biosynthesis, and virulence were summarized. Potential effectors were predicted from the proteome of these Ganoderma species/strains, and putative effectors that were being expressed in G. boninense in oil palm roots but not found in other species were identified. The findings provide a useful resource to further analyze plant-pathogenesis and wood degradation activities of these Ganoderma species.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
DOI Number: https://doi.org/10.3390/f14030653
Publisher: Multidisciplinary Digital Publishing Institute
Keywords: Effector prediction; Ganoderma; Orthologs; Plant-pathogenesis; Comaparative genomics; Effectors; Life on land
Depositing User: Ms. Nur Faseha Mohd Kadim
Date Deposited: 17 Oct 2024 07:06
Last Modified: 17 Oct 2024 07:06
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/f14030653
URI: http://psasir.upm.edu.my/id/eprint/107078
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