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Iron overload in anaemia with underlying haemoglobin constant spring in an antenatal mother in primary care


Citation

Thew, Hui Zhu and Ng, Chee Han and Loo, Cheng Yee (2024) Iron overload in anaemia with underlying haemoglobin constant spring in an antenatal mother in primary care. BMJ Case Reports, 17 (2). art. no. 258526. ISSN 1757-790X

Abstract

This is the case of a gravida 3 para 1 woman in her late 20s with underlying haemoglobin constant spring who visited a healthcare clinic for an antenatal check-up. Towards the end of her second trimester, she experienced lethargy. During her antenatal booking, she was diagnosed with mild asymptomatic anaemia, high serum ferritin, T saturation of 88 and abnormal liver function tests. She was referred to a hospital where an MRI scan revealed over 2 g of iron deposits in her liver, leading to a revised diagnosis of iron overload. Treatment included deferoxamine and expectant management throughout her antenatal period, and her delivery was uncomplicated. While iron deficiency anaemia is common in pregnancy, it is crucial not to overlook iron deposition and the distinction from acute fatty liver during pregnancy to prevent treatment delays.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1136/bcr-2023-258526
Publisher: BMJ
Keywords: Anemia; Anemia; Iron-deficiency; Female; Hemoglobins; Abnormal; Humans; Iron; Iron overload; Mothers; Pregnancy; Pregnancy complications; Hematologic; Primary health care; Alanine aminotransferase; Aspartate aminotransferase; Bilirubin; Ferritin; Ferrous fumarate; Hemoglobin; Transferrin; Hemoglobin constant spring; Hemoglobin variant; Iron; Activated partial thromboplastin time; Adult; Alanine aminotransferase blood level; Anemia; Article; Aspartate aminotransferase blood level; Bilirubin blood level; Blood transfusion; Case report; Clinical article; Drug withdrawal; Erythrocyte concentrate; Fatty liver; Female; Fetus movement; Follow up; Hemoglobin blood level; Human; Human cell; Hypertransaminasemia; Iron chelation; Iron overload; Lethargy; Leukocyte count; Liver function test; Male; Medical history; Patient referral; Prenatal care; Prothrombin time; Second trimester pregnancy; Splenomegaly; Third trimester pregnancy; Ultrasound; Vaginal delivery; Young adult; Anemia; Complication; Iron deficiency anemia; Iron overload; Mother; Pregnancy; Pregnancy complication; Primary health care
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 18 Nov 2024 02:12
Last Modified: 18 Nov 2024 02:12
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1136/bcr-2023-258526
URI: http://psasir.upm.edu.my/id/eprint/106096
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