UPM Institutional Repository

Simulation of mechanical heart valve dysfunction and the non-newtonian blood model approach


Citation

Chen, Aolin and Basri, Adi Azriff and Ismail, Norzian and Tamagawa, Masaaki and Zhu, Di and Ahmad, Kamarul Arifin (2022) Simulation of mechanical heart valve dysfunction and the non-newtonian blood model approach. Applied Bionics and Biomechanics, 2022. art. no. 9612296. pp. 1-14. ISSN 1176-2322; ESSN: 1754-2103

Abstract

The mechanical heart valve (MHV) is commonly used for the treatment of cardiovascular diseases. Nonphysiological hemodynamic in the MHV may cause hemolysis, platelet activation, and an increased risk of thromboembolism. Thromboembolism may cause severe complications and valve dysfunction. This paper thoroughly reviewed the simulation of physical quantities (velocity distribution, vortex formation, and shear stress) in healthy and dysfunctional MHV and reviewed the non-Newtonian blood flow characteristics in MHV. In the MHV numerical study, the dysfunction will affect the simulation results, increase the pressure gradient and shear stress, and change the blood flow patterns, increasing the risks of hemolysis and platelet activation. The blood flow passes downstream and has obvious recirculation and stagnation region with the increased dysfunction severity. Due to the complex structure of the MHV, the non-Newtonian shear-thinning viscosity blood characteristics become apparent in MHV simulations. The comparative study between Newtonian and non-Newtonian always shows the difference. The shear-thinning blood viscosity model is the basics to build the blood, also the blood exhibiting viscoelastic properties. More details are needed to establish a complete and more realistic simulation.


Download File

Full text not available from this repository.
Official URL or Download Paper: https://www.hindawi.com/journals/abb/2022/9612296/

Additional Metadata

Item Type: Article
Divisions: Faculty of Engineering
Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1155/2022/9612296
Publisher: Hindawi Publishing
Keywords: Mechanical Heart Valve (MHV); Cardiovascular; Thromboembolism; Newtonian
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 23 Nov 2023 04:57
Last Modified: 23 Nov 2023 04:57
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2022/9612296
URI: http://psasir.upm.edu.my/id/eprint/103203
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item