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A systemic review and recommendation for an autopsy approach to death followed the COVID 19 vaccination


Citation

Tan, Lii Jye and Koh, Cai Ping and Lai, Shau Kong and Poh, Woon Cheng and Othman, Mohammad Shafie and Hussin, Huzlinda (2022) A systemic review and recommendation for an autopsy approach to death followed the COVID 19 vaccination. Forensic Science International, 340. art. no. 111469. pp. 1-16. ISSN 0379-0738

Abstract

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in December 2019. An immediate prevention approach for the outbreak is the development of a vaccination program. Despite a growing number of publications showing the effectiveness of vaccination in preventing SARS-CoV-2 outbreak and reducing the mortality rate, substantial fatal adverse effects were reported after vaccination. Confirmation of the causal relationship of death is required to reimburse under the national vaccination program and could provide a reference for the selection of vaccination. However, a lack of guidelines in the laboratory study and autopsy approach hampered the investigation of post-vaccination death. In this paper, we performed a systematic electronic search on scientific articles related to severe Covid-19 vaccination adverse effects and approaches in identifying the severe side effects using PubMed and Cochrane libraries. A summary on the onset, biochemistry changes and histopathological analyzes of major lethally side effects post-vaccination were discussed. Ultimately, a checklist is suggested to improve the quality of investigation.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1016/j.forsciint.2022.111469
Publisher: Elsevier
Keywords: COVID19; Vaccine; Myocarditis; Thrombosis; Anaphylaxis; Adverse effects
Depositing User: Ms. Nur Faseha Mohd Kadim
Date Deposited: 23 Nov 2023 08:41
Last Modified: 23 Nov 2023 08:41
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.forsciint.2022.111469
URI: http://psasir.upm.edu.my/id/eprint/100476
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