Search for New Antioxidants and Other Related Bioactive Compounds from Zingiberaceous Species

Mohamad, Habsah (2002) Search for New Antioxidants and Other Related Bioactive Compounds from Zingiberaceous Species. PhD thesis, Universiti Pertanian Malaysia.

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Abstract

Thirty-one species from Zingiberacea family were screened for their antioxidant (FTC method), antimicrobial (disc diffusion method), and antitumour promoting (EBV EA assay method) activities. Three species, A lpinia zerumbet, A lpinia rfflesiana and Etlingera elatiar, were selected for further study, based on their promising preliminary biological activities. Five known compounds were isolatpd hom the rhizomes of Alpinia zerumbet, namely S,6-dehydrokawain, flavokawin B, l,7-diphenyl-Shydroxy- 6-heptene-3-one, (-)-pinocembrin, and a mixture of stigmasterol and β-sitosterol. From the fruits of Alpinia raffiesiana, seven compounds were isolated, namely 5,6-dehydrokawain: flavokawin B, l,7-diphenyl-5- hydroxy-6-heptene-3-one, (-)-pinocembrin, cardamonin, (-)-pinostrobin, and 2',3',4',6' -tetrahydroxychalcone. This is the first report on the isolation of 2',3',4',6' -tetrahydroxychalcone from Alpinia.

Item Type:Thesis (PhD)
Subject:Zingiberaceae
Subject:Antioxidants
Subject:Bioactive compounds
Chairman Supervisor:Associate Professor Dr. Md. Nordin Hj. Lajis, PhD
Call Number:FSAS 2002 55
Faculty or Institute:Faculty of Environmental Studies
ID Code:9525
Deposited By: Muizzudin Kaspol
Deposited On:14 Feb 2011 01:35
Last Modified:29 Oct 2012 01:06

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