Citation
Rad, Javad Sharifi and Quispe, Cristina and Herrera Bravo, Jesús and Belén, Lisandra Herrera and Kaur, Rajandeep and Kregiel, Dorota and Uprety, Yadav and Beyatli, Ahmet and Yeskaliyeva, Balakyz and Kırkın, Celale and Özçelik, Beraat and Sen, Surjit and Acharya, Krishnendu and Sharopov, Farukh and Martins, Natália Cruz and Kumar, Manoj and Abdull Razis, Ahmad Faizal and Sunusi, Usman and Muhammad Kamal, Ramla and Shaheen, Shabnum and Suleria, Hafiz Ansar Rasul
(2021)
Glycyrrhiza Genus: enlightening phytochemical components for pharmacological and health-promoting abilities.
Oxidative Medicine and Cellular Longevity, 2021 (spec.).
art. no. 7571132.
pp. 1-20.
ISSN 1942-0994
Abstract
The Glycyrrhiza genus, generally well-known as licorice, is broadly used for food and medicinal purposes around the globe. The genus encompasses a rich pool of bioactive molecules including triterpene saponins (e.g., glycyrrhizin) and flavonoids (e.g., liquiritigenin, liquiritin). This genus is being increasingly exploited for its biological effects such as antioxidant, antibacterial, antifungal, anti-inflammatory, antiproliferative, and cytotoxic activities. The species Glycyrrhiza glabra L. and the compound glycyrrhizin (glycyrrhizic acid) have been studied immensely for their effect on humans. The efficacy of the compound has been reported to be significantly higher on viral hepatitis and immune deficiency syndrome. This review provides up-to-date data on the most widely investigated Glycyrrhiza species for food and medicinal purposes, with special emphasis on secondary metabolites’ composition and bioactive effects.
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