UPM Institutional Repository

A systematic review of antimicrobial peptides from fish with anticancer properties


Citation

Najm, Ahmed Abdulkareem and Azfaralarriff, Ahmad and Dyari, Herryawan Ryadi Eziwar and Syed Alwi, Sharifah Sakinah and Khalili, Nahid and Othman, Babul Airianah and Law, Douglas and Shahid, Muhammad and Fazry, Shazrul (2022) A systematic review of antimicrobial peptides from fish with anticancer properties. Pertanika Journal of Science and Technology, 30 (2). pp. 1171-1196. ISSN 0128-7680; ESSN: 2231-8526

Abstract

Fish is a potential source of various forms of bioactive compounds. It can be used as a source of specific proteins, especially in medicine. Recently, studies related to the use of antimicrobial peptides (AMPs) from fish are being carried out to find an alternative cure for cancer. To achieve this objective, the AMP used must meet a condition where it possesses the ability to target tumor cells without affecting the normal cell. Therefore, this study aims to systematically review and classify the recent AMPs isolated from fish and their therapeutic activities, focusing on their anticancer and antimicrobial activities. A systematic review of studies published in English between 2017 and 2020 was conducted in PubMed NCBI, Biomed Central, Science Direct, and Google Scholar databases using keywords and inclusion and exclusion criteria. A systematic review conducted has identified 38 potential AMPs isolated from fish that have been reported to have antimicrobials activity. Of all of these, 21 AMPs also have anticancer properties. Therefore, it is important to continue to explore and study natural ingredients in developing new approaches in medicine. This research is essential to enable the potential of AMPs to be identified and applied.


Download File

[img] Text
18 JST-2979-2021.pdf

Download (824kB)

Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.47836/pjst.30.2.18
Publisher: Universiti Putra Malaysia Press
Keywords: Antimicrobial peptides; Antitumor activity; Fish; Medicinal agents
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 27 May 2022 22:28
Last Modified: 27 May 2022 22:28
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.47836/pjst.30.2.18
URI: http://psasir.upm.edu.my/id/eprint/92591
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item