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Discovery and development of novel anti-fungal peptides against foodspoiling fungi


Citation

Muhialdin, Belal J. and Algboory, Hussein L. and Mohammed, Nameer K. and Kadum, Hana and Meor Hussin, Anis Shobirin and Saari, Nazamid and Hassan, Zaiton (2020) Discovery and development of novel anti-fungal peptides against foodspoiling fungi. Current Drug Discovery Technologies, 17 (4). 553 - 561. ISSN 1570-1638; ESSN: 1875-6220

Abstract

Despite the extensive research carried out to develop natural antifungal preservatives for food applications, there are very limited antifungal agents available to inhibit the growth of spoilage fungi in processed foods. Scope and Approach: Therefore, this review summarizes the discovery and development of antifungal peptides using lactic acid bacteria fermentation to prevent food spoilage by fungi. The focus of this review will be on the identification of antifungal peptides, potential sources, the possible modes of action and properties of peptides considered to inhibit the growth of spoilage fungi. Key Findings and Conclusions: Antifungal peptides generated by certain lactic acid bacteria strains have a high potential for applications in a broad range of foods. The mechanism of peptides antifungal activity is related to their properties such as low molecular weight, concentration and secondary structure. The antifungal peptides were proposed to be used as bio-preservatives to reduce and/or replace chemical preservatives.


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Official URL or Download Paper: https://www.eurekaselect.com/173472/article

Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
Halal Products Research Institute
DOI Number: https://doi.org/10.2174/1570163816666190715120038
Publisher: Bentham Science Publishers
Keywords: Bio-preservation; Antifungal peptides; Drug discovery; Food applications; Mode of action; Natural preservatives
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 23 Dec 2021 08:27
Last Modified: 23 Dec 2021 08:27
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.2174/1570163816666190715120038
URI: http://psasir.upm.edu.my/id/eprint/88482
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