UPM Institutional Repository

Co-infections of Tilapia Lake Virus, Aeromonas hydrophila and Streptococcus agalactiae in farmed red hybrid tilapia


Basri, Lukman and Md Nor, Roslindawani and Salleh, Annas and Md Yasin, Ina Salwany and Saad, Mohd Zamri and Abd Rahaman, Nor Yasmin and Barkham, Timothy and Azmai, Mohammad Noor Amal (2020) Co-infections of Tilapia Lake Virus, Aeromonas hydrophila and Streptococcus agalactiae in farmed red hybrid tilapia. Animals, 10 (11). pp. 1-12. ISSN 2076-2615


A high death rate among red hybrid tilapias was observed in a farm in Selangor, Malaysia, in January 2020. The affected fish appeared lethargic, isolated from schooling group, showed loss of appetite, red and haemorrhagic skin, exophthalmia and enlarged gall bladders. Histopathological assessment revealed deformation of kidney tubules, and severe congestion with infiltrations of inflammatory cells in the brains and kidneys. Syncytial cells and intracytoplasmic inclusion bodies were occasionally observed in the liver and brain sections. Tilapia Lake Virus (TiLV), Aeromonas hydrophila and Streptococcus agalactiae were identified in the affected fish, either through isolation or through PCR and sequencing analysis. The phylogenetic tree analysis revealed that the TiLV strain in this study was closely related to the previously reported Malaysian strain that was isolated in 2019. On the other hand, A. hydrophila and S. agalactiae were closer to Algerian and Brazilian strains, respectively. The multiple antibiotic resistance index for A. hydrophila and S. agalactiae was 0.50 and 0.25, respectively. Co-infections of virus and bacteria in cultured tilapia is a new threat for the tilapia industry.

Download File

[img] Text (Abstract)

Download (5kB)
Official URL or Download Paper: https://www.mdpi.com/2076-2615/10/11/2141

Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture
Faculty of Science
Faculty of Veterinary Medicine
Institute of Bioscience
DOI Number: https://doi.org/10.3390/ani10112141
Publisher: Multidisciplinary Digital Publishing Institute
Keywords: Co-infections; Tilapia Lake Virus; Aeromonas hydrophila; Streptococcus agalactiae; Tilapia
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 10 Mar 2022 07:44
Last Modified: 10 Mar 2022 07:44
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/ani10112141
URI: http://psasir.upm.edu.my/id/eprint/88185
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item