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Nodal histiocytic disorder in children: report of three cases and review of literature


Ainer, Indumathi and Gendeh, Hardip Singh and Husain, Salina and Mohd Nor, Khadijah (2020) Nodal histiocytic disorder in children: report of three cases and review of literature. Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 36. art. no. 33. pp. 1-5. ISSN 2090-0740; ESSN: 2090-3405


Background: Histiocytic system consists of phagocytes and dendritic cells. Both are found in lymph nodes. Usually, this disorder presents with painless cervical lymph node enlargement hence frequently mistaken for lymphoma or tuberculosis. Case presentation: Here, we report three pediatric cases: one of Langerhans cell histiocytosis and two of sinus histiocytosis and massive lymphadenopathy with neck mass as initial presentation. The final diagnosis was made with fine needle aspiration cytology, biopsy, and ancillary tests. Conclusion: Biopsy and immunohistochemistry studies are recommended for determining subtypes of histiocytosis and further management of patient.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1186/s43163-020-00035-z
Publisher: Springer
Keywords: Histiocytosis; Lymphadenopathy; Histopathology; Children; Langerhans cell; Case report
Depositing User: Mohamad Jefri Mohamed Fauzi
Date Deposited: 03 Jan 2022 02:56
Last Modified: 03 Jan 2022 02:56
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1186/s43163-020-00035-z
URI: http://psasir.upm.edu.my/id/eprint/86909
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