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Isolation, Identification and Bioactivity of Natural Products from Melaleuca Cajuputi (Myrtacea)


Ul Hassan, Vaqar (1996) Isolation, Identification and Bioactivity of Natural Products from Melaleuca Cajuputi (Myrtacea). Masters thesis, Universiti Pertanian Malaysia.

Abstract / Synopsis

In this study the components of aerial and subterranean parts of Melaleuca cajuputi were isolated and identified. Chemical investigation on the leaves resulted in the isolation of two known triterpenoids, betulinic acid and u rsolic acid ester. The oily fractions contained two phenolic components, a naphthalene dione, an anthracene carboxal-dehyde and a phenenthracene analogy. Methanol extracts of the bark, seeds, and flowers allowed for the isolation and identification of betulinic acid, urolic acid and betuline, respectively. Their structures were determined using m odern spectroscopic techniques such as IR, NMR, MS and by comparison with literature.The bioassay was carried out on crude extracts of leaves, roots, seeds, and bark against first in star mosquito larvae (Aedes albopictus) according to the procedure described in the literature. These extracts were found to be acute or relatively toxic to the target organisms. Extract from leaves exhibited the highest toxicity followed by extracts from roots, seeds, and bark respectively.

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Additional Metadata

Item Type: Thesis (Masters)
Subject: Melaleuca quinquenervia.
Subject: Spectrum analysis.
Call Number: FSAS 1996 8
Chairman Supervisor: Associate Professor Faujan bin Haji Ahmad, PhD
Divisions: Faculty of Environmental Studies
Depositing User: Nurul Hayatie Hashim
Date Deposited: 03 Dec 2010 12:38
Last Modified: 11 Jun 2012 15:35
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