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Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties


Ahmad, Haslina and Zaharudin, Nurul Syahira and Abdul Majid, Nur Nadia and Jumbri, Khairulazhar and Abdul Rahman, Mohd Basyaruddin (2019) Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 54 (2). pp. 124-132. ISSN 2289-7879


A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline phenylacetate, choline ricinoleate and choline trichloroacetate. Result obtained from FT-IR, 1H and 13C NMR, mass spectrometry, thermogravimetric and differential scanning calorimetry confirmed the formation of these cholinium-based ILs. These ILs were then tested for their anti-microbial properties towards seven types of bacteria which consist of three Gram-positive bacteria, Bacillus subtilis (B29), Staphylococcus aureus (S276), Staphylococcus epidermidis (S273), two Gram-negative bacteria, Pseudomonas aeruginosa (ATCC 15442) and Escherichia coli (E266) and two types of yeasts, Candida albicans (9002) and Candida tropicalis (A3).Interestingly, all of the choliniumILs possess excellent antimicrobial activity as good as the standard, Streptomycin. The most significant antimicrobial activity was observed in choline phenylacetate against all seven types of bacteria tested in this study.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
Publisher: Penerbitan Akademia Baru
Keywords: Lonic liquids; Antimicrobial; Cholinium; Neutralization reaction
Depositing User: Mr. Sazali Mohamad
Date Deposited: 16 Oct 2020 20:28
Last Modified: 16 Oct 2020 20:28
URI: http://psasir.upm.edu.my/id/eprint/82339
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