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Resistance gene cloning from a wild crop relative by sequence capture and association genetics


Arora, Sanu and Steuernagel, Burkhard and Gaurav, Kumar and Chandramohan, Sutha and Long, Yunming and Matny, Oadi and Johnson, Ryan and Enk, Jacob and Periyannan, Sambasivam and Singh, Narinder and Md Hatta, M. Asyraf and Athiyannan, Naveenkumar and Cheema, Jitender and Yu, Guotai and Kangara, Ngonidzashe and Ghosh, Sreya and Szabo, Les J. and Poland, Jesse and Bariana, Harbans and Jones, Jonathan D. G. and Bentley, Alison R. and Ayliffe, Mick and Olson, Eric and Xu, Steven S. and Steffenson, Brian J. and Lagudah, Evans and Wulff, Brande B. H. (2019) Resistance gene cloning from a wild crop relative by sequence capture and association genetics. Nature Biotechnology, 37 (2). pp. 139-143. ISSN 1087-0156; ESSN: 1546-1696


Disease resistance (R) genes from wild relatives could be used to engineer broad-spectrum resistance in domesticated crops. We combined association genetics with R gene enrichment sequencing (AgRenSeq) to exploit pan-genome variation in wild diploid wheat and rapidly clone four stem rust resistance genes. AgRenSeq enables R gene cloning in any crop that has a diverse germplasm panel.

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Official URL or Download Paper: https://www.nature.com/articles/s41587-018-0007-9

Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture
DOI Number: https://doi.org/10.1038/s41587-018-0007-9
Publisher: Nature Research
Keywords: Agricultural genetics; Plant biotechnology; Plant molecular biology
Depositing User: Mr. Sazali Mohamad
Date Deposited: 08 Sep 2021 02:44
Last Modified: 08 Sep 2021 02:44
Altmetrics: http://www.altmetrics.com/details.php?domain=pasir.upm.edu.my&doi=10.1038/s41587-018-0007-9
URI: http://psasir.upm.edu.my/id/eprint/81994
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