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Quantification of multi-classes of endocrine-disrupting compounds in estuarine water


Ismail, Nur Afifah Hanun and Wee, Sze Yee and Kamarulzaman, Nitty Hirawaty and Aris, Ahmad Zaharin (2019) Quantification of multi-classes of endocrine-disrupting compounds in estuarine water. Environmental Pollution, 249. pp. 1019-1028. ISSN 0269-7491; ESSN: 1873-6424


Emerging pollutants known as endocrine-disrupting compounds (EDCs) are a contemporary global issue, especially in aquatic ecosystems. As aquaculture production through mariculture activities in Malaysia supports food production, the concentration and distribution of EDCs in estuarine water ecosystems may have changed. Therefore, this current study aims to prepare a suitable and reliable method for application on environmental samples. Besides, this study also presented the occurrence of EDCs pollutant in Pulau Kukup, Johor, where the biggest and most active mariculture site in Malaysia takes place. Analytical methods based on a combination of solid-phase extraction with liquid chromatography tandem mass spectrometry (Solid-phase extraction (SPE)-LC-MS/MS) have been modified and optimised to examine the level of targeted EDCs contaminant. In the current study, this method displays high extraction recovery for targeted EDCs, ranging from 92.02% to 132.32%. The highest concentration detected is diclofenac (<0.47–79.89 ng/L) followed by 17β-estradiol (E2) (<5.28–31.43 ng/L) and 17α-ethynylestradiol (EE2) (<0.30–7.67 ng/L). The highest percentage distribution for the targeted EDCs in the current study is diclofenac, followed by EE2 and dexamethasone with the percentages of 99.44%, 89.53% and 73.23%, respectively. This current study can be a baseline assessment to understand the pollution profile of EDCs and their distribution in the estuarine water of the mariculture site throughout the world, especially in Malaysia. Owing to the significant concentration of targeted EDCs detected.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture
Faculty of Science and Environmental Studies
DOI Number: doi.org/10.1016/j.envpol.2019.03.089
Publisher: Elsevier
Keywords: Endocrine disrupting compounds; Mariculture site; Solid-phase extraction; Estuarine water; Liquid chromatography mass spectrometer
Depositing User: Mr. Sazali Mohamad
Date Deposited: 17 Oct 2020 15:19
Last Modified: 17 Oct 2020 15:19
Altmetrics: http://www.altmetric.com/details.php?domain=psair.upmedu.my&doi=doi.org/10.1016/j.envpol.2019.03.089
URI: http://psasir.upm.edu.my/id/eprint/81908
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