Citation
Rusli, Nur Syahfinaz Hidayah and Zakaria, Faikah and Anwar Basha, Farahnaz Ahmad and Abdul Razak, Hairil Rashmizal
(2019)
Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study.
Malaysian Journal of Fundamental and Applied Sciences, 15 (6).
pp. 772-775.
ISSN 2289-5981; ESSN: 2289-599X
Abstract
This research study aimed to evaluate metabolites in human skeletal muscles pre- and post-exercise non-invasively via proton magnetic resonance spectroscopy (¹H-MRS). The upper legs of 6 lightly active male subjects underwent imaging pre- and post-exercise via 1.5 T MRI (TR/TE = 3500ms/100ms, FOV = 20cm, slice thickness = 6mm) and ¹H-MRS (TR/TE = 2000ms/31ms, VOI = 20mm x 20mm x 35mm). The researchers measured the pre- and post-exercise metabolic readings (NAA, CHO, and Cr metabolites) for the vastus lateralis and semitendinosus muscles. A paired t-test was performed. In the vastus lateralis muscle, NAA, CHO, and Cr metabolites values decreased with no significant difference after the exercise. Similarly, in the semitendinosus muscle, NAA, CHO, and Cr metabolites values were also decreased with CHO (p<0.02) and Cr (p<0.01) showed the significant difference after the exercise. Evaluating human skeletal muscles via ¹H-MRS at 1.5 T is feasible.
Download File
|
Text
Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla.pdf
Download (9kB)
|
|
Additional Metadata
Actions (login required)
|
View Item |