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Nanomedicines for cancer therapy: current status, challenges and future prospects


Bor, Gizem and Mat Azmi, Intan Diana and Yaghmur, Anan (2019) Nanomedicines for cancer therapy: current status, challenges and future prospects. Therapeutic delivery, 10 (2). pp. 113-132. ISSN 2041-5990; ESSN: 2041-6008


The emergence of nanomedicine as an innovative and promising alternative technology shows many advantages over conventional cancer therapies and provides new opportunities for early detection, improved treatment, and diagnosis of cancer. Despite the cancer nanomedicines' capability of delivering chemotherapeutic agents while providing lower systemic toxicity, it is paramount to consider the cancer complexity and dynamics for bridging the translational bench-to-bedside gap. It is important to conduct appropriate investigations for exploiting the tumor microenvironment, and achieving a more comprehensive understanding of the fundamental biological processes in cancer and their roles in modulating nanoparticle-protein interactions, blood circulation, and tumor penetration. This review provides an overview of the current cancer nanomedicines, the major challenges, and the future opportunities in this research area.

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Official URL or Download Paper: https://pubmed.ncbi.nlm.nih.gov/30678550/

Additional Metadata

Item Type: Article
Divisions: Faculty of Science
DOI Number: https://doi.org/10.4155/tde-2018-0062
Publisher: Future Science
Keywords: Biological barriers; Cancer nanomedicines; Chemotherapeutic agents; Drug delivery; Nanoparticles; Tumor microenvironment
Depositing User: Ms. Nida Hidayati Ghazali
Date Deposited: 31 Jan 2021 14:48
Last Modified: 31 Jan 2021 14:48
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.4155/tde-2018-0062
URI: http://psasir.upm.edu.my/id/eprint/81452
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