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Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus)


Ahmad, Ali Anwar and Abd Wahab, Norsham and Yeo, Wenjing Clara and Yin, Serena Jocelyn Oh Wai and Chen, Hui Cheng (2019) Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus). Journal of Veterinary Medical Science, 81 (1). pp. 48-52. ISSN 0916-7250; ESSN: 1347-7439


Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg. There were no significant differences in the time from anesthetic injection to induction and intubation between the A-M and T-Z groups. The time from the injection of reversal in the A-M group and the time from cessation of isoflurane in the T-Z group to extubation, first response to recovery and ambulation were longer (P<0.05) in the T-Z group. The T-Z group recorded lower (P<0.05) rectal temperatures compared to the A-M group. This study showed that both drug combinations can be used effectively for the immobilization of civets. The A-M combination provided better anesthetic depth, but with higher incidence of bradycardia and hypoxemia. The recovery time was reduced significantly as atipamezole was used as a reversal agent in the A-M combination.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Veterinary Medicine
DOI Number: https://doi.org/10.1292/jvms.18-0297
Publisher: Japanese Society of Veterinary Science
Keywords: Alfaxalone-medetomidine; Common palm civet; Paradoxurus musangus; Tiletamine-zolazepam
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 14 Oct 2020 20:37
Last Modified: 14 Oct 2020 20:37
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1292/jvms.18-0297
URI: http://psasir.upm.edu.my/id/eprint/80978
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