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Antioxidant compounds and capacities of Gac (Momordica cochinchinesis Spreng) fruits


Abdulqader, Ali and Ali, Faisal and Ismail, Amin and Mohd Esa, Norhaizan (2019) Antioxidant compounds and capacities of Gac (Momordica cochinchinesis Spreng) fruits. Asian Pacific Journal of Tropical Biomedicine, 9 (4). pp. 158-167. ISSN 2221-1691; ESSN: 2588-9222


Objective: To identify and determine the composition of antioxidant compounds, and to evaluate the antioxidant abilities of Gac fruit parts (peel, pulp, seed and aril) grown in Malaysia. Methods: LC-MS/MS was used for identification of antioxidant compounds and UV-Vis for estimation of the contents of phenolics, flavonoids, and carotenoids. Lycopene and 毬-carotene were quantified using high-performance liquid chromatography. DPPH (2, 2-diphenyl-1- picrylhydrazyl) and ferric reducing antioxidant power assays were employed to evaluate antioxidant capacities. Results: Phytochemicals were found amongst all the fruit parts. Notably, significant amounts of carotenoids [(107.4 ± 4.5), (85.7 ± 4.4), (110.6 ± 2.1) mg/100 g dry weight (DW)], and relatively high levels of both phenolics [(27.3 ± 1.7), (28.9 ± 2.4), (30.8 ± 2.7) mg/100 g DW] and flavonoids [(38.1 ± 2.2), (8.8 ± 1.3), (24.5 ± 3.3) mg/100 g DW] were found in the fruit’s peel, pulp and aril, respectively. Seed part also showed a relatively high level of flavonoids [(18.1 ± 2.3) mg/100 g DW]. Lycopene and 毬-carotene were found to be significantly high (P < 0.05) in aril [(579.3 ± 22.7) and (621.0 ± 35.0) µg/g DW], followed by peel [(51.0 ± 7.5) and (210.0 ± 12.5) μg/g DW] and pulp [(37.6 ± 10.9) and (205.6 ± 22.1) μg/g DW)]. Antioxidant assays revealed that aril possessed the highest scavenging activity (IC50 = 865 μg/mL), while the peel possessed the highest ferric reducing power of 140 µmol FeSO4/µg. Conclusions: The current results demonstrate that Gac fruit grown in Malaysia is a rich source of phytochemicals, especially carotenoids, and possesses antioxidant activities. Thus, such findings suggest Gac fruit as a source of an antioxidant plant.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Institute of Bioscience
DOI Number: https://doi.org/10.4103/2221-1691.256729
Publisher: Medknow Publications and Media
Keywords: Momordica cochinchinensis; Phytochemicals; Carotenoids; Antioxidants; Polyphenols; High-performance liquid chromatography
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 12 Nov 2020 00:42
Last Modified: 12 Nov 2020 00:42
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.4103/2221-1691.256729
URI: http://psasir.upm.edu.my/id/eprint/80681
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