Citation
Mah, Siau Hui and Ee, Gwendoline Cheng Lian and Teh, Soek Sin and Rahmani, Mawardi and Lim, Yang Mooi and Go, Rusea
(2012)
Phylattrin, a new cytotoxic xanthone from Calophyllum soulattri.
Molecules, 17 (7).
pp. 8303-8311.
ISSN 1420-3049
Abstract
Our continuing studies on secondary metabolites from the stem bark of Calophyllum soulattri has led to the isolation of another new diprenylated xanthone, phylattrin (1), in addition to five other xanthones and two common sterols. The xanthones are soulattrin (2), caloxanthone C (3), macluraxanthone (4), brasixanthone B (5) and trapezifolixanthone (6) while the sterols are stigmasterol (7) and β-sitosterol (8). The structures of these compounds were determined on the basis of spectroscopic analyses such as 1D and 2D-NMR, HRESIMS, IR and UV. Compounds 1–7 exhibited moderate cytotoxic activities against SNU-1, HeLa, Hep G2, NCI-H23, K562, Raji, LS174T, IMR-32 and SK-MEL-28 cells.
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Official URL or Download Paper: https://www.mdpi.com/1420-3049/17/7/8303
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Science |
| DOI Number: | https://doi.org/10.3390/molecules17078303 |
| Publisher: | MDPI |
| Keywords: | Calophyllum soulattri; Clusiaceae; Cytotoxic; Phylattrin; Xanthone |
| Depositing User: | Nabilah Mustapa |
| Date Deposited: | 01 Jun 2020 03:11 |
| Last Modified: | 01 Jun 2020 03:11 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/molecules17078303 |
| URI: | http://psasir.upm.edu.my/id/eprint/77981 |
| Statistic Details: | View Download Statistic |
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