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Two new xanthones from Calophyllum nodusum (Guttiferae)


Mad Nasir, Nadiah and Rahmani, Mawardi and Shaari, Khozirah and Ee, Gwendoline Cheng Lian and Go, Rusea and Kassim, Nur Kartinee and Mohamad, Siti Noor Kamilah and Che Jamil, Mohamad Johadi Iskandar (2011) Two new xanthones from Calophyllum nodusum (Guttiferae). Molecules, 16 (11). pp. 8973-8980. ISSN 1420-3049


The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone (1a) and trapezifolixanthone A (2). Other common terpenoids such as betulinic acid, lupeol, stigmasterol and friedelin were also isolated from the extracts and identified. The structures of the compounds were established by detailed spectral analysis and comparison with previously reported data.

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Official URL or Download Paper: https://www.mdpi.com/1420-3049/16/11/8973

Additional Metadata

Item Type: Article
Divisions: Faculty of Science
DOI Number: https://doi.org/10.3390/molecules16118973
Publisher: MDPI
Keywords: Calophyllum nodusum; Nodusuxanthone; Trapezifolixanthone A; Lupeol; Stigmasterol
Depositing User: Nabilah Mustapa
Date Deposited: 04 May 2020 17:52
Last Modified: 04 May 2020 17:52
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/molecules16118973
URI: http://psasir.upm.edu.my/id/eprint/77961
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