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Pilonidal sinus: why does it recur


Rahoma, Ahmed Hussein (2009) Pilonidal sinus: why does it recur. Malaysian Journal of Medicine and Health Sciences, 5 (2). pp. 69-77. ISSN 1675-8544


Introduction: Ring formation, a structural chromosomal abnormality, is frequently observed in X chromosome. This article reports the 45,X along with 46,X, r(X) cell lines and its associations to the observed phenotypic features in an Indian female proband aged 15 years. Methods: The karyotype was determined from peripheral lymphocyte culture and Giemsa-Trypsin banding technique. Results: The karyotype was 45,X/46,X,r(X) (p11q13) (18%82%). The presence of 45,X and ring X in mosaicism status indicates that the karyotype is a Turner syndrome variant. The variably manifested phenotypic features in the proband could be due to the presence of single X, the lost segments in ring X and the mosaicism status for the X. Conclusion: During counseling, proband’s chromosomal status and its effect were explained to the proband’s parents. Parents were also counselled about the importance of medical management, education and career to the proband.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: Recurrent pilonidal sinus; Surgery and prevention
Depositing User: Mohd Zulkifly Othman
Date Deposited: 19 Aug 2010 07:41
Last Modified: 07 Oct 2015 08:58
URI: http://psasir.upm.edu.my/id/eprint/7744
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