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A new cytotoxic carbazole alkaloid from Clausena excavata


Yap, Taufiq Yun Hin and Peh, Tian Hai and Ee, Gwendoline Cheng Lian and Rahmani, Mawardi and Md. Sukari, Mohd Aspollah and Ali, Abdul Manaf and Muse, Radzali (2007) A new cytotoxic carbazole alkaloid from Clausena excavata. Natural Product Research, 21 (9). pp. 810-813. ISSN 1478-6419; ESSN: 1478-6427

Abstract / Synopsis

A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1),together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
DOI Number:
Publisher: Taylor & Francis
Keywords: Clausena excavata; Rutaceae; Stem bark; Carbazole alkaloid; Anticancer activity
Depositing User: Najwani Amir Sariffudin
Date Deposited: 09 Aug 2010 07:44
Last Modified: 24 Nov 2016 08:42
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