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Japanese Encephalitis in Malaysia: an overview and timeline


Citation

Kumar, Kiven and Arshad, Siti Suri and Selvarajah, Gayathri Thevi and Abu, Jalila and Ooi, Peck Toung and Abba, Yusuf and Abd. Rahaman, Nor Yasmin and Bande, Faruku and Sharma, Reuben and Ong, Bee Lee (2018) Japanese Encephalitis in Malaysia: an overview and timeline. Acta Tropica, 185. 219 - 229. ISSN 0001-706X, ESSN: 1873-6254

Abstract

Japanese encephalitis (JE) is a vector-borne zoonotic disease caused by the Japanese encephalitis virus (JEV). It causes encephalitis in human and horses, and may lead to reproductive failure in sows. The first human encephalitis case in Malaya (now Malaysia) was reported during World War II in a British prison in 1942. Later, encephalitis was observed among race horses in Singapore. In 1951, the first JEV was isolated from the brain of an encephalitis patient. The true storyline of JE exposure among humans and animals has not been documented in Malaysia. In some places such as Sarawak, JEV has been isolated from mosquitoes before an outbreak in 1992. JE is an epidemic in Malaysia except Sarawak. There are four major outbreaks reported in Pulau Langkawi (1974), Penang (1988), Perak and Negeri Sembilan (1998–1999), and Sarawak (1992). JE is considered endemic only in Sarawak. Initially, both adults and children were victims of JE in Malaysia, however, according to the current reports; JE infection is only lethal to children in Malaysia. This paper describes a timeline of JE cases (background of each case) from first detection to current status, vaccination programs against JE, diagnostic methods used in hospitals and factors which may contribute to the transmission of JE among humans and animals in Malaysia.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Veterinary Medicine
DOI Number: https://doi.org/10.1016/j.actatropica.2018.05.017
Publisher: Elsevier
Keywords: Japanese encephalitis; Outbreak; Human; Animals; Malaysia
Depositing User: Mr. Sazali Mohamad
Date Deposited: 04 Dec 2019 13:42
Last Modified: 04 Dec 2019 13:42
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.actatropica.2018.05.017
URI: http://psasir.upm.edu.my/id/eprint/74770
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