UPM Institutional Repository

Antifungal compound isolated from Catharanthus roseus L. (pink) for bological control of root rot rubber diseases


Halimoon, Normala and Ahmad, Mohd Farid and Ling, Sui Kiong and Zahari, Rizal (2018) Antifungal compound isolated from Catharanthus roseus L. (pink) for bological control of root rot rubber diseases. International Journal of Analytical Chemistry. art. no. 8150610. pp. 1-7. ISSN 1687-8760; ESSN: 1687-8779


Rigidoporus microporus, Ganoderma philippii, and Phellinus noxius are root rot rubber diseases and these fungi should be kept under control with environmentally safe compounds from the plant sources. Tus, an antifungal compound isolated from Catharanthus roseus was screened for its efectiveness in controlling the growth of these fungi. Te antifungal compound isolated from C. roseus extract was determined through thin layer chromatography (TLC) and nuclear magnetic resonance (NMR) analysis. Each C. roseus of the DCM extracts was marked as CRD1, CRD2, CRD3, CRD4, CRD5, CRD6, and CRD7, respectively. TLC results showed that all of the C. roseus extracts peaked with red colour at Rf = 0.61 at 366 nm wavelength, except for CRD7. Te CRD4 extract was found to be the most efective against R. microporus and G. philippii with inhibition zones of 3.5 and 1.9 mm, respectively, compared to that of other extracts. Tese extracts, however, were not efective against P. noxius. Te CRD4 extract contained ursolic acid that was detected by NMR analysis and the compound could be developed as a biocontrol agent for controlling R. microporus and G. philippii. Moreover, little or no research has been done to study the effectiveness of C. roseus in controlling these fungi.

Download File

Additional Metadata

Item Type: Article
Divisions: Faculty of Environmental Studies
Institute of Tropical Forestry and Forest Products
DOI Number: https://doi.org/10.1155/2018/8150610
Publisher: Hindawi Limited
Keywords: Hevea brasiliensis; Antifungal; Root rot diseases
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 26 Jan 2021 19:55
Last Modified: 26 Jan 2021 19:55
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2018/8150610
URI: http://psasir.upm.edu.my/id/eprint/73156
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item