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Effect of consumption heated oils with or without dietary cholesterol on the cevelopment of atherosclerosis


Citation

Che Idris, Che Anishas and Sundram, Kalyana and Abdull Razis, Ahmad Faizal (2018) Effect of consumption heated oils with or without dietary cholesterol on the cevelopment of atherosclerosis. Nutrients, 10 (10). pp. 1-11. ISSN 2072-6643; ESSN: 2072-6643

Abstract

Heating oils and fats for a considerable length of time results in chemical reactions, leading to the aggravation of a free radical processes, which ultimately contributes to atherosclerosis. Our study focused on elucidating the effect of feeding heated oils with or without dietary cholesterol on the development of atherosclerosis in rabbits. We heated palm olein and corn oil at 180 °C for 18 h and 9 h per day, respectively, for two consecutive days. Next, 20 male rabbits were divided into four groups and fed the following diet for 12 weeks: (i) heated palm olein (HPO); (ii) HPO with cholesterol (HPOC); (iii) heated corn oil (HCO); and (iv) HCO with cholesterol (HCOC). Plasma total cholesterol (TC) was significantly lower in the HCO group compared to the HCOC group. Atherosclerotic lesion scores for both fatty plaques and fatty streaks were significantly higher in the HCO and HCOC groups as compared to the HPO and HPOC groups. Additionally, fibrous plaque scores were also higher in the HCO and HCOC groups as compared to the HPO and HPOC groups. These results suggest that heated palm oil confers protection against the onset of atherosclerosis compared to heated polyunsaturated oils in a rabbit model.


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Official URL or Download Paper: https://www.mdpi.com/2072-6643/10/10/1527

Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
Institute of Bioscience
Institute of Tropical Agriculture and Food Security
DOI Number: https://doi.org/10.3390/nu10101527
Publisher: MDPI
Keywords: Heated fats; Cholesterol; Atherosclerosis; Corn oil; Palm olein
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 02 Jun 2020 00:28
Last Modified: 02 Jun 2020 00:28
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/nu10101527
URI: http://psasir.upm.edu.my/id/eprint/72390
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