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A case of myeloid sarcoma masquerading as neuroblastoma


Hassan, Siti Amirah and Sivaratnam, Dhashani and Devaraj, Navin Kumar and Teh, Kok Hoi and Abdul Razak, Rosniza and Ching, Siew Mooi (2019) A case of myeloid sarcoma masquerading as neuroblastoma. Malaysian Journal of Medicine and Health Sciences, 15 (2). pp. 157-159. ISSN 1675-8544; ESSN: 2636-9346


Myeloid sarcoma (MS) is an uncommon type of malignancy, and its diagnosis is comparable to acute myeloid leukaemia (AML). In the rare circumstances in which MS does present without AML, it is known as MS de novo. We report a case of a 10-month old child who presented with bilateral proptosis and a pelvic mass due to synchronous primary MS de novo. She was initially misdiagnosed with neuroblastoma, which has this typical presentation. The histopathological result from the biopsy of the orbital mass also showed a small blue round cell tumour (SBRCT) as seen in cases of neuroblastoma. However, the diagnosis of MS was confirmed using immunohistochemistry (IHC) from the orbital biopsy specimen, which usually plays a major role in the diagnosis of orbital tumours and as a prognostic indicator. Our patient remains in clinical remission two years after antileukemic treatment, with no relapse or progression to AML.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: Proptosis; Neuroblastoma; Myeloid sarcoma; Immunohistochemistry
Depositing User: Nabilah Mustapa
Date Deposited: 04 Jul 2019 04:59
Last Modified: 04 Jul 2019 04:59
URI: http://psasir.upm.edu.my/id/eprint/69564
Statistic Details: View Download Statistic

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