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Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression


Citation

Loke, Wai Keong and Mohd Saud, Halimi (2009) Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression. In: 8th Malaysia Congress on Genetics, 4-6 Aug. 2009, Genting Highlands, Malaysia. (pp. 402-406).

Abstract / Synopsis

Chromobacterium violaceum is a pathogenic bacteria to human and produce antibiotics which include aerocyanidine, aerocavin, 3,6-dihydroxyindoxazene, Factor Y-T0678H (6-hydroxy-3-oxo-1,2-benzisoxazolin) and violacein, a purple pigment that gives Chromobacterium violaceum its colour. The production of purple pigment and antibiotics were controlled by quorum sensing and activated by N-acyl homoserine lactones (AHL) C6-HSL signal molecules in high cell density condition and reaches the quorum level. In high concentration of glucose, the production of purple pigment and antibiotics from C. violaceum was affected and was produced only at low nondetectable volume. This phenomenon showed that catabolite repression happened in C. violaceum and the operon to control the genes of production of purple pigment and other antibiotics were catabolite-sensitive where the operon was not maximally expressed.


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Additional Metadata

Item Type: Conference or Workshop Item (Poster)
Divisions: Faculty of Agriculture
Institute of Tropical Agriculture
Keywords: Chromobacterium violaceum; Catabolite repression
Depositing User: Nabilah Mustapa
Date Deposited: 04 Sep 2018 12:14
Last Modified: 04 Sep 2018 12:14
URI: http://psasir.upm.edu.my/id/eprint/65141
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