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Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency


Citation

Mat Rusni, Izyani and Ismail, Alyani (2017) Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency. In: 2017 6th International Conference on Electrical Engineering and Informatics (ICEEI), 25-27 Nov. 2017, Langkawi, Kedah. .

Abstract

In this paper, the interest of microwave signals for biological detection applications using metamaterial structure as a biosensor element has been demonstrated. Microwave sensing is highly challenging for biological detection as it presents the attractive advantages of being contactless, non-invasive at low power level and yet its label free. The resonant frequency of the sensor is measured as 4.96 GHz. The shift in resonant frequency is employed as the sensor output for deoxyribonucleic acid (DNA) detection. The resonance frequency is shifted to the left when single stranded deoxyribonucleic acid (ssDNA) is immobilized onto gold surface and further shifted when hybridization or the binding event between the molecule of ssDNA and cDNA occurred. The sensitivity of this biosensor is up to 10 MHz/Molar with the detection limit of Molar is conducted during this experiment.


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Additional Metadata

Item Type: Conference or Workshop Item (Paper)
Divisions: Faculty of Engineering
DOI Number: https://doi.org/10.1109/ICEEI.2017.8312402
Publisher: IEEE
Keywords: Microwave biosensor; Metamaterial; Split ring resonator; Hybridization; DNA sensing
Depositing User: Nabilah Mustapa
Date Deposited: 13 Aug 2018 03:16
Last Modified: 13 Aug 2018 03:16
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1109/ICEEI.2017.8312402
URI: http://psasir.upm.edu.my/id/eprint/64639
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