Simple Search:

Engineering lipase for structure and function relationship study


Ahmad Kamarudin, Nor Hafizah and Ahmad, Nurul Nadirah and Leow, Adam Thean Chor and Raja Abdul Rahman, Raja Noor Zaliha (2017) Engineering lipase for structure and function relationship study. In: 5th International Symposium on Applied Engineering and Sciences (SAES2017), 14-15 Nov. 2017, Universiti Putra Malaysia. (p. 17).

Abstract / Synopsis

Lipase has long been recognized as one the most important industrial enzymes and bring about a diverse range of bioconversion reactions in both aqueous and non-aqueous media. The various biotechnological potential of lipase especially those of microbial origins are associated with their intrinsic properties such as stability in various pH and temperature, and the ability to remain active in various organic solvents. Despite their industrial potentials, natural enzymes are often not suitable for biocatalytic processes, hence knowledge on the structure and function correlation is important to manipulate the enzymes to suit the industrial needs. Previously, an organic solvent stable bacteria producing lipase was isolated from a car service area. This lipase exhibited high activity and stability in alkaline pH, low temperature and a wide range of organic solvents. In this work, strategies were conducted using computational and prediction tools in order to identify the key features responsible for the enzyme’s stability. Knowledge gained could be useful in lipase engineering study.

Download File

PDF (Abstract)
BIO Poster 111117 17.pdf

Download (190kB) | Preview

Additional Metadata

Item Type: Conference or Workshop Item (Poster)
Divisions: Faculty of Biotechnology and Biomolecular Sciences
Keywords: Lipase; Industrial enzyme; Lipase engineering
Depositing User: Nabilah Mustapa
Date Deposited: 04 Jul 2018 10:38
Last Modified: 04 Jul 2018 10:38
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item