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Anti-diabetic activities of Hibiscus cannabinus extracts leaves and roots in vitro study


M. K., Zuraida and A., Zalinah and Hamid, Muhajir and I., Maznah (2008) Anti-diabetic activities of Hibiscus cannabinus extracts leaves and roots in vitro study. In: Biodiversity and Biotechnology Symposium 2008, 19-21 Nov. 2008, Kuching, Sarawak, Malaysia. (pp. 247-250).


Hibiscus cannabinus (Kenaf) is an annual herbaceous crop of the Malvaceae family. This plant is composed of various active components including tannins, saponins, polyphenolic, alkaloid, essential oil and steroid, has long been prescribed in traditional folk medicine in India and Africa. The aqueous leaf extract of this plant has been demonstrated to be haematically active and anti-oxidative. The underlying mechanisms that account for Kenaf pharmacology and active components however remain to be elucidated. This experiment was conducted to identify the active compounds of H.cannabinus extracts which had an anti-diabetic activity. There were yields of Hibiscus cannabinus extract which are 28.33% (80% ethanol leaves extract) and 42.23% (hot water leaves extract), 6.62% (80% ethanol extract) and 11.95% (hot water extract). H.cannabinus extracts enhanced insulin secretion in BRIN BD11 cells higher than Glibenclamide (100uM) except 80% ethanol H. cannabinus leaves extract at concentration 1000 ug/ml.

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Additional Metadata

Item Type: Conference or Workshop Item (Paper)
Divisions: Faculty of Biotechnology and Biomolecular Sciences
Faculty of Medicine and Health Science
Institute of Bioscience
Publisher: Sarawak Biodiversity Centre
Keywords: Hibiscus cannabinus; Anti-diabetic; Roots extracts; Leaves extract
Depositing User: Nabilah Mustapa
Date Deposited: 04 Jul 2018 02:31
Last Modified: 04 Jul 2018 02:31
URI: http://psasir.upm.edu.my/id/eprint/64266
Statistic Details: View Download Statistic

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