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The roles of miRNAs in human breast cancer and canine mammary tumor


Yu, Richard Ming Chuan and Cheah, Yoke Kqueen (2017) The roles of miRNAs in human breast cancer and canine mammary tumor. Applied Cancer Research, 37. art. no. 37. pp. 1-11. ISSN 1980-5578


MicroRNAs have become a hot topic in cancer research nowadays due to their important role not only on cancer development, progression, invasion but also on repression of cancer related genes. With advanced technologies, these microRNAs can easily be detected from biopsy samples and blood for early diagnosis, prognosis and treatment. Due to increasing demand of research in exploring expression profile of microRNAs with respect to different subtypes of breast cancer, this review aimed to provide an update on microRNA database available resources, canine breast cancer models, the role of microRNA as oncomir or oncosupressor, detection of microRNAs and potential of miRNAs for breast cancer treatment.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1186/s41241-017-0043-7
Publisher: BioMed Central
Keywords: Breast cancer; MicroRNAs; Oncomir; Oncosupressor; Targets of miRNA; Breast cancer model; miRNA profiles; miRNA database
Depositing User: Mohd Hafiz Che Mahasan
Date Deposited: 05 Nov 2018 00:52
Last Modified: 29 Jan 2019 23:51
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1186/s41241-017-0043-7
URI: http://psasir.upm.edu.my/id/eprint/63529
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