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Plants of the genus Zingiber as a source of bioactive phytochemicals: from tradition to pharmacy


Sharifi-Rad, Mehdi and Varoni, Elena Maria and Salehi, Bahare and Sharifi-Rad, Javad and Matthews, Karl R and Ayatollahi, Seyed Abdulmajid and Kobarfard, Farzad and Ibrahim, Salam A and Mnayer, Dima and Zakaria, Zainul Amiruddin and Sharifi-Rad, Majid and Yousaf, Zubaida and Iriti, Marcello and Basile, Adriana and Rigano, Daniela (2017) Plants of the genus Zingiber as a source of bioactive phytochemicals: from tradition to pharmacy. Molecules, 22 (12). pp. 1-20. ISSN 1420-3049; ESSN: 1431-5165


Plants of the genus Zingiber (Family Zingiberaceae) are widely used throughout the world as food and medicinal plants. They represent very popular herbal remedies in various traditional healing systems; in particular, rhizome of Zingiber spp. plants has a long history of ethnobotanical uses because of a plethora of curative properties. Antimicrobial activity of rhizome essential oil has been extensively confirmed in vitro and attributed to its chemical components, mainly consisting of monoterpene and sesquiterpene hydrocarbons such as α-zingiberene, ar-curcumene, β-bisabolene and β-sesquiphellandrene. In addition, gingerols have been identified as the major active components in the fresh rhizome, whereas shogaols, dehydrated gingerol derivatives, are the predominant pungent constituents in dried rhizome. Zingiber spp. may thus represent a promising and innovative source of natural alternatives to chemical food preservatives. This approach would meet the increasing concern of consumers aware of the potential health risks associated with the conventional antimicrobial agents in food. This narrative review aims at providing a literature overview on Zingiber spp. plants, their cultivation, traditional uses, phytochemical constituents and biological activities.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.3390/molecules22122145
Publisher: MDPI AG
Keywords: Zingiber; Essential oil; Food preservatives; Ginger; Herbal remedies; Rhizome; Traditional healing systems
Depositing User: Mas Norain Hashim
Date Deposited: 08 Nov 2022 03:59
Last Modified: 08 Nov 2022 03:59
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/molecules22122145
URI: http://psasir.upm.edu.my/id/eprint/62770
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