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Review on fatty acid desaturases and their roles in temperature acclimatisation


Citation

Garba, Lawal and Mohamad Ali, Mohd Shukuri and Oslan, Siti Nurbaya and Raja Abdul Rahman, Raja Noor Zaliha (2017) Review on fatty acid desaturases and their roles in temperature acclimatisation. Journal of Applied Sciences, 17 (6). pp. 282-295. ISSN 1812-5654; ESSN: 1812-5662

Abstract

Carbohydrates and proteins are polymers of polysaccharides and polypeptide residues, respectively. Conversely, lipids are made up of a wide range of compounds with tremendous differences in structures and lack building blocks. Therefore, fatty acids constitute the major components of various lipid classes such as glycerides and sphingolipids. Fatty acids are organic compounds containing a carboxylic acid group mostly at the end of an aliphatic chain and are categorized into saturated and unsaturated. Most fatty acids especially the so-called polyunsaturated fatty acids (PUFAs) and their derivatives play key biological roles in inflammatory response, cell division, control of lipid metabolism, as signaling molecules, supply of energy and protecting the biological membranes structure and function. In this study, a general overview of fatty acids, their biosynthesis mechanisms as well as biological importance have been discussed. Fatty acid desaturase enzymes and their sources have also been reviewed. Recent studies on the functional expression of different types of desaturase enzymes have also been discussed.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
DOI Number: https://doi.org/10.3923/jas.2017.282.295
Publisher: Asian Network for Scientific Information
Keywords: Fatty acid desaturases; Unsaturated fatty acids; Functional expression; Membrane fluidity; Temperature acclimatisation
Depositing User: Nabilah Mustapa
Date Deposited: 07 Jun 2018 06:24
Last Modified: 07 Jun 2018 06:24
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3923/jas.2017.282.295
URI: http://psasir.upm.edu.my/id/eprint/60514
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