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An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia


Omar, Nazri and Abdul Muna'aim, Maimunah and Md. Saleh, Rafidah and Mohd Kasim, Zaidah and Mohd Isa, Muhammad (2017) An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia. Malaysian Journal of Medicine and Health Sciences, 13 (2). pp. 47-57. ISSN 1675-8544


Introduction: Microbial keratitis (MK) is an important cause for corneal blindness and understanding its risk factors enable us to improve management and minimise its complications. Methods: In this retrospective case review, medical records of all patients treated for MK from 2006 to 2013 was analysed to know the socio-demography, preceding risk factors, clinical characteristics, causative organisms and final visual outcome. Results: A total of 174 patients (180 eyes) were included in this study. Identifiable ocular risk factors included contact lens (CL) usage (85, 47.2%), ocular trauma (50, 27.8%), ocular surface disease (21, 11.6%), steroid use (6, 3.3%) and immuno-compromy (19, 10.5%). Association factors for presenting uncorrected visual acuity (UCVA) were age group (p=0.013), size (p<0.001), location (p<0.001) and hypopyon (p<0.001). The predictors for final best spectacle-corrected visual acuity (BSCVA) were age group (p<0.001), nationality (p=0.020), occupation (p<0.001), CL use (p<0.001), ocular surface disease (p=0.048), size (p<0.001) and location (p<0.044), hospitalisation duration (p=0.002) and presenting UCVA (p<0.001). Conclusions: Contact lens was the most frequent predisposing risk factor for microbial keratitis, followed by ocular trauma. Understanding the association factors for presenting vision and predictors for final vision may help in the patients’ management and improve eventual outcome of microbial keratitis.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: Microbial keratitis; Corneal ulcer; Contact lens; Pseudomonas aeruginosa; Visual outcome
Depositing User: Nabilah Mustapa
Date Deposited: 05 Jan 2018 03:02
Last Modified: 26 Jan 2018 09:43
URI: http://psasir.upm.edu.my/id/eprint/58283
Statistic Details: View Download Statistic

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